7-Hydroxy-1,2,3,4-tetrahydroquinoline

CAS: 58196-33-1

Ref. 3D-FH42272

Product Information

• Name: 7-Hydroxy-1,2,3,4-tetrahydroquinoline
• Synonyms: 1,2,3,4-Tetrahydro-7-hydroxyquinoline, 1,2,3,4-Tetrahydro-7-quinolinol, 1,2,3,4-Tetrahydroquinolin-7-Ol, 1,2,3,4-Tetrahydroquinolin-8-Ol, 7-Quinolinol, 1,2,3,4-tetrahydro-, 7-hydroxy-1,2,3,4-Tetrahydro-quinolin

Description

7-Hydroxy-1,2,3,4-tetrahydroquinoline (7OH-THQ) is a fluorophore that can be used to detect the presence of cancer cells. It is a linker and labile and can be synthesized from the lactam 7-hydroxypyrazolo-[4,3-a]pyridin-5(6H)-one. The synthesis of 7OH-THQ is possible by reacting 4-(dimethylamino)benzenesulfonyl chloride with 2,2'-dithiolethane in the presence of sodium hydroxide. 7OH-THQ has been shown to be effective as an anticancer drug in vitro assays for colon and breast cancer cells. It also has fluorescence properties that are sensitive to acidic conditions and pH levels.

• Brand: Biosynth

Chemical properties

• Molecular weight: 149.19 g/mol
• Formula: C₉H₁₁NO
• Purity: Min. 96 Area-%
• Color/Form: Powder
• InChI: InChI=1S/C9H11NO/c11-8-4-3-7-2-1-5-10-9(7)6-8/h3-4,6,10-11H,1-2,5H2
• InChI key: InChIKey=HJJRGZMJZDSMDB-UHFFFAOYSA-N
• SMILES: Oc1ccc2c(c1)NCCC2