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5-(4-Hydroxyphenyl)-3H-1,2-dithiole-3-thione
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5-(4-Hydroxyphenyl)-3H-1,2-dithiole-3-thione

CAS: 18274-81-2

Ref. 3D-FH46502

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Estimated delivery in United States, on Thursday 2 Jan 2025

Product Information

Name:
5-(4-Hydroxyphenyl)-3H-1,2-dithiole-3-thione
Synonyms:
  • 4-Hydroxyanethole trithione
  • Desmethyl-adt
  • Desmethylanethol dithiolthione
  • 3H-1,2-Dithiole-3-thione, 5-(4-hydroxyphenyl)-
  • 4-(5-sulfanyl-3H-1,2-dithiol-3-ylidene)cyclohexa-2,5-dien-1-one
Description:

Kaurane diterpenoids are a class of natural products that have been shown to be potent inhibitors of inflammatory bowel disease. Ent-kaurane diterpenoid 5-(4-hydroxyphenyl)-3H-1,2-dithiole-3-thione (5KD) is one such example. It has been shown to inhibit the release of inflammatory mediators such as prostaglandin E2 and nitric oxide from human colonic cells. The mechanism by which 5KD inhibits inflammation is not yet fully understood, but it may involve blocking the activation of cyclooxygenase enzymes or inhibiting the synthesis of proinflammatory cytokines such as tumor necrosis factor alpha and interleukin 1 beta. 5KD also has demonstrated activity against cancerous cells in vitro and in vivo, suggesting an application for cancer therapy.

Notice:
Our products are intended for lab use only. For any other use, please contact us.
Brand:
Biosynth
Long term storage:
Notes:

Chemical properties

Molecular weight:
226.34 g/mol
Formula:
C9H6OS3
Purity:
Min. 95%
InChI:
InChI=1S/C9H6OS3/c10-7-3-1-6(2-4-7)8-5-9(11)13-12-8/h1-5,10H
InChI key:
InChIKey=IWBBKLMHAILHAR-UHFFFAOYSA-N
SMILES:
Oc1ccc(-c2cc(=S)ss2)cc1
MDL:
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Hazard Info

UN Number:
EQ:
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H Statements:
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Forbidden to fly:
Hazard Info:
Packing Group:
LQ:

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