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N-α-Z-L-histidine

CAS:

Ref. 3D-FH47279

5g
135.00€
10g
190.00€
25g
254.00€
N-α-Z-L-histidine
Biosynth

Product Information

Name:N-α-Z-L-histidine
Synonyms:
  • Z-L-His-OH
Brand:Biosynth
Description:N-alpha-Z-L-histidine is a nitrogenous compound that is an amide formed by the reaction of histidine and trifluoroacetic acid. It has been shown to be anticancer and to have an effect on tumor vasculature, with efficacy against solid tumors. N-alpha-Z-L-histidine inhibits the cell cycle at the G1 phase and blocks DNA synthesis, which arrests cells in the M phase. This drug also inhibits tumor angiogenesis by blocking vascular endothelial growth factor (VEGF) signaling. N-alpha-Z-L-histidine is a molecule that has been synthesized using solid phase chemistry and purified by high performance liquid chromatography.
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Chemical properties

Molecular weight:289.29 g/mol
Formula:C14H15N3O4
Purity:Min. 95%
Color/Form:Powder
InChI:InChI=1S/C14H15N3O4/c18-13(19)12(6-11-7-15-9-16-11)17-14(20)21-8-10-4-2-1-3-5-10/h1-5,7,9,12H,6,8H2,(H,15,16)(H,17,20)(H,18,19)/t12-/m0/s1
InChI key:InChIKey=WCOJOHPAKJFUDF-LBPRGKRZSA-N
SMILES:O=C(N[C@@H](Cc1cnc[nH]1)C(=O)O)OCc1ccccc1

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