N-alpha-Z-hydrazide

CAS: 5331-43-1

Ref. 3D-FH48384

Product Information

• Name: N-alpha-Z-hydrazide
• Synonyms: Z-NHNH2Benzyloxycarbonylhydrazine, (+)-Biotin N-hydroxysuccinimide ester, Benzyl hydrazinecarboxylate, Benzyl hydrazinocarboxylate, Benzyloxycarbonyl hydrazide, Carbazic acid, benzyl ester, Carbobenzoxyhydrazide, Carbobenzyloxyhydrazine, Hydrazincarboxylic acid benzyl ester, Hydrazinecarboxylic Acid Benzyl Ester, Hydrazinecarboxylic acid, phenylmethyl ester, N-(Benzyloxycarbonyl)hydrazine, NSC 2287, Phenylmethyl hydrazinecarboxylate, [(Benzyloxy)carbonyl]hydrazine

Description

N-alpha-Z-hydrazide is a cyclic peptide that is active against bacterial infections, including infectious diseases and autoimmune diseases. It has been shown to be effective against mouse models of inflammatory bowel disease, multiple sclerosis, and arthritis. The compound is also used as an experimental model for studying the effects of drugs on biological systems. N-alpha-Z-hydrazide binds to the Mcl-1 protein in a coordinated geometry that prevents its interaction with other proteins. This binding leads to cell death by preventing the release of cytochrome C from mitochondria and reducing mitochondrial membrane potential. N-alpha-Z-hydrazide has demonstrated antiinflammatory activity in mice which may be due to its inhibition of prostaglandin synthesis.

• Brand: Biosynth

Chemical properties

• Molecular weight: 166.18 g/mol
• Formula: C₈H₁₀N₂O₂
• Purity: Min. 95%
• Color/Form: Powder