N-α-Z-DL-histidine

CAS: 19728-57-5

Ref. 3D-FH49626

Product Information

• Name: N-α-Z-DL-histidine
• Synonyms: Z-DL-His-OH, Cbz-DL-histidine

Description

N-alpha-Z-DL-histidine (NZ) is an amino acid derivative that has been shown to inhibit the synthesis of inflammatory genes. It also inhibits fatty acid uptake in rat brain and may be used as a potential treatment for obesity. NZ has been shown to have an inhibitory effect on the metabolism of dopamine, leading to increased levels of this neurotransmitter in the brain. The asymmetric synthesis of NZ may result in a more active form than L-histidine, which is the natural form of histidine.

NZ can bind with MK-801, which is a ligand for NMDA receptors. This binding prevents MK-801 from binding to these receptors and activating them, thereby inhibiting the effects of this drug on bladder function and other physiological processes.

NZ has been found to inhibit photosynthetic pigment production in plants, such as chlorophylls and carotenoids, by interfering with their biosynthesis pathways. It also

• Brand: Biosynth

Chemical properties

• Molecular weight: 289.29 g/mol
• Formula: C₁₄H₁₅N₃O₄
• Purity: Min. 95%
• InChI: InChI=1S/C14H15N3O4/c18-13(19)12(6-11-7-15-9-16-11)17-14(20)21-8-10-4-2-1-3-5-10/h1-5,7,9,12H,6,8H2,(H,15,16)(H,17,20)(H,18,19)
• InChI key: InChIKey=WCOJOHPAKJFUDF-UHFFFAOYSA-N
• SMILES: O=C(NC(Cc1cnc[nH]1)C(=O)O)OCc1ccccc1