5-Hydroxyoxindole

CAS: 3416-18-0

Ref. 3D-FH52473

Product Information

• Name: 5-Hydroxyoxindole
• Synonyms: 5-Hydroxy-1,3-dihydro-indol-2-one, 1,3-Dihydro-5-hydroxy-2H-indol-2-one, 2-Indolinone, 5-hydroxy-, 2H-Indol-2-one, 1,3-dihydro-5-hydroxy-, 5-Hydroxyindolin-2-One, 5-hydroxy-1,3-dihydro-2H-indol-2-one, Oxindole, 5-hydroxy-

Description

5-Hydroxyoxindole (5HO) is a naturally occurring molecule that is found in oxindole and other indoles. It has been shown to have regulatory effects on inflammatory diseases, notably in the treatment of colitis. 5HO possesses significant cytotoxicity against carcinoma cells and also has radical scavenging activity. This compound can be synthesized using a solid-phase synthesis method. The presence of 5HO in skin cells has been correlated with the production of skin pigment called melanin. In addition, this molecule has been shown to bind to picolinic acid, which may contribute to its anti-inflammatory properties. 5HO is also present in neurologic disorders such as Alzheimer's disease, Parkinson's disease, and amyotrophic lateral sclerosis.

• Brand: Biosynth

Chemical properties

• Molecular weight: 149.15 g/mol
• Formula: C₈H₇NO₂
• Purity: Min. 95%
• Color/Form: Beige Powder
• InChI: InChI=1S/C8H7NO2/c10-6-1-2-7-5(3-6)4-8(11)9-7/h1-3,10H,4H2,(H,9,11)
• InChI key: InChIKey=ZGTUSQAQXWSMDW-UHFFFAOYSA-N
• SMILES: O=C1Cc2cc(O)ccc2N1