Harmol

CAS: 487-03-6

Ref. 3D-FH57643

Product Information

• Name: Harmol
• Synonyms: 1-Methyl-9H-beta-carbolin-7-ol, 1-Methyl-9H-pyrido(3,4-b)indol-7-ol, 207-645-9, 9H-Pyrido[3,4-b]indol-7-ol, 1-methyl-, NSC 72292

Description

Harmol is a natural product that exhibits cytotoxic activity against various human tumor cell lines. Harmol inhibits the enzyme activities of survivin, which is a protein that promotes apoptosis and suppresses autophagy. It has been shown to inhibit the growth of murine hepatoma cells in vitro. Harmol also inhibits calcium pantothenate-mediated mitochondrial membrane potential and chlorogenic acid-induced redox potential.

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• Brand: Biosynth

Chemical properties

• Molecular weight: 198.22 g/mol
• Formula: C₁₂H₁₀N₂O
• Purity: Min. 95%
• Color/Form: Off-White Powder
• InChI: InChI=1S/C12H10N2O/c1-7-12-10(4-5-13-7)9-3-2-8(15)6-11(9)14-12/h2-6,13-14H,1H3
• InChI key: InChIKey=LBBJNGFCXDOYMQ-UHFFFAOYSA-N
• SMILES: Cc1[nH]ccc2c1[nH]c1cc(=O)ccc12