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(S)-5-Hydroxypiperidin-2-one
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(S)-5-Hydroxypiperidin-2-one

CAS: 24211-54-9

Ref. 3D-FH59583

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Estimated delivery in United States, on Tuesday 14 Jan 2025

Product Information

Name:
(S)-5-Hydroxypiperidin-2-one
Synonyms:
  • 2-Piperidinone,5-hydroxy-, (S)-
  • 2-Piperidone, 5-hydroxy-, stereoisomer (8CI)
  • (S)-5-Hydroxy-2-piperidinone
Description:

(S)-5-Hydroxypiperidin-2-one is a chiral compound that is used in the synthesis of tofacitinib. It can be obtained by nitroaldol reaction of L-tyrosine with dimethylzinc, which yields the racemic mixture of (R)- and (S)-isomers. The stereoselective synthesis of (S) 5-hydroxypiperidin-2-one also requires the use of chiral reagents such as enantioselective catalysts or diastereoselective reagents. This compound has been shown to have anti-inflammatory properties in an animal model.

Notice:
Our products are intended for lab use only. For any other use, please contact us.
Brand:
Biosynth
Long term storage:
Notes:

Chemical properties

Molecular weight:
115.13 g/mol
Formula:
C5H9NO2
Purity:
Min. 95%
InChI:
InChI=1S/C5H9NO2/c7-4-1-2-5(8)6-3-4/h4,7H,1-3H2,(H,6,8)/t4-/m0/s1
InChI key:
InChIKey=GPRZVNYVEZZOKH-BYPYZUCNSA-N
SMILES:
O=C1CC[C@H](O)CN1
MDL:
Melting point:
Boiling point:
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Density:
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EINECS:
Merck:
HS code:

Hazard Info

UN Number:
EQ:
Class:
H Statements:
P Statements:
Forbidden to fly:
Hazard Info:
Packing Group:
LQ:

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