1-(2-Hydroxyphenyl)-2-nitroethene
CAS: 3156-43-2
Ref. 3D-FH65831
| 25mg | 147.00 € | ||
| 50mg | 197.00 € | ||
| 100mg | 351.00 € | ||
| 250mg | 589.00 € |
Product Information
- 2'-Hydroxy-beta-Nitrostyrene
1-(2-Hydroxyphenyl)-2-nitroethene is an organocatalytic biomolecule that has been synthesized in an asymmetric fashion. The synthesis of the molecule relies on a squaramide and the use of intramolecular hydrogen transfer reactions to create a nitro group. The molecule was used to generate antiestrogenic activity in MDA-MB-231 breast cancer cells and MCF-7 breast cancer cells by inhibiting estrogen receptor alpha (ERα) transcriptional activity. This molecule has also been shown to be bifunctional, as it inhibits both protein kinase C (PKC) and mitogen-activated protein kinase (MAPK) signaling pathways when applied to these cell lines. X-ray crystal structures of the molecule have been obtained with orientations that exhibit different degrees of hydrophobicity, which may be due to interactions with water molecules.
Chemical properties
Technical inquiry about: 3D-FH65831 1-(2-Hydroxyphenyl)-2-nitroethene
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