5-Hydroxy-6-methoxyindole-carboxylic acid

CAS: 2495-80-9

Ref. 3D-FH66276

Product Information

• Name: 5-Hydroxy-6-methoxyindole-carboxylic acid
• Synonyms: 1H-indole-2-carboxylic acid, 5-hydroxy-6-methoxy-

Description

5-Hydroxy-6-methoxyindole-carboxylic acid (5-HMICA) is a molecule that is found in the pericardium and urine of patients with cancer. 5-HMICA has been shown to suppress tumor growth and activate cell mediated cytotoxicity in vitro. It also induces T helper type 1 (Th1) immune responses, which are associated with the production of cytokines such as interferon gamma and tumor necrosis factor alpha.

5-HMICA has been shown to have anti-cancer properties by inducing tumor cell death through a number of mechanisms including modulation of antioxidant enzymes, suppression of DNA repair, inhibition of proliferation, and induction of apoptosis. 5-HMICA also suppresses suppressor genes involved in tumorigenesis and stimulates eumelanin synthesis for skin pigmentation.

• Brand: Biosynth

Chemical properties

• Molecular weight: 207.18 g/mol
• Formula: C₁₀H₉NO₄
• Color/Form: Powder
• InChI: InChI=1S/C10H9NO4/c1-15-9-4-6-5(3-8(9)12)2-7(11-6)10(13)14/h2-4,11-12H,1H3,(H,13,14)
• InChI key: InChIKey=FWKJNOVLYWGWCH-UHFFFAOYSA-N
• SMILES: COc1cc2[nH]c(C(=O)O)cc2cc1O