Product Information
- 2′-Hydroxy-3-nitrochalcone
- 2-Propen-1-one, 1-(2-hydroxyphenyl)-3-(3-nitrophenyl)-
- Chalcone, 2′-hydroxy-3-nitro-
- 1-(2-Hydroxyphenyl)-3-(3-nitrophenyl)-2-propen-1-one
2'-Hydroxy-3-nitrochalcone is a yellow crystalline solid that has been shown to have an antiviral effect against HIV and herpes simplex virus. The crystal structure of 2'-hydroxy-3-nitrochalcone has been determined using x-ray crystallography. The compound is structurally similar to other antiviral agents, such as acyclovir, valacyclovir, and penciclovir.
2'-Hydroxy-3-nitrochalcone inhibits the viral DNA polymerase by competing with the nucleotide cofactor at the enzyme active site. This leads to a reduction in viral DNA synthesis and an inhibition of cell proliferation.
Chemical properties
Technical inquiry about: 3D-FH66866 2'-Hydroxy-3-nitrochalcone
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