4-Hydroxybenzylidene acetophenone

CAS: 20426-12-4

Ref. 3D-FH70053

Product Information

• Name: 4-Hydroxybenzylidene acetophenone
• Synonyms: 4-Hydroxychalcone, (2E)-3-(4-hydroxyphenyl)-1-phenylprop-2-en-1-one, (4-Hydroxybenzal)acetophenone, (4-Hydroxybenzylidene)acetophenone, 1-Phenyl-3-(4-hydroxyphenyl)-2-propen-1-one, 2-Propen-1-one, 3-(4-hydroxyphenyl)-1-phenyl-, 3-(4-Hydroxyphenyl)-1-Phenylprop-2-En-1-One, 3-(4-Hydroxyphenyl)-1-phenyl-2-propen-1-one, 4-Hydroxybenzylideneacetophenone, 4-Hydroxystyryl phenyl ketone, Chalcone, 4-hydroxy-, NSC 60593, p-Hydroxychalcone

Description

4-Hydroxybenzylidene acetophenone is a natural compound that has been shown to exhibit cytotoxic activity against human cancer cells. It inhibits the production of TNF-α and reactive oxygen species, and increases mitochondrial membrane potential in MCF-7 cells. The mechanism of action of 4-Hydroxybenzylidene acetophenone involves binding to the heme group of cytochrome P450 and altering its reactivity. This compound has been proposed as a possible analytical method for determining the amount of reactive oxygen species present in biological samples.

• Brand: Biosynth

Chemical properties

• Molecular weight: 224.25 g/mol
• Formula: C₁₅H₁₂O₂
• Purity: Min. 95%
• Color/Form: Powder
• InChI: InChI=1S/C15H12O2/c16-14-9-6-12(7-10-14)8-11-15(17)13-4-2-1-3-5-13/h1-11,16H/b11-8+
• InChI key: InChIKey=PWWCDTYUYPOAIU-DHZHZOJOSA-N
• SMILES: O=C(/C=C/c1ccc(O)cc1)c1ccccc1