2-Hydroxy-5-methylbenzamide

CAS: 39506-61-1

Ref. 3D-FH71075

Product Information

• Name: 2-Hydroxy-5-methylbenzamide
• Synonyms: 5-Methylsalicyamide
• Brand: Biosynth
• Description: Labetalol is a β-blocker that is used to treat high blood pressure. Labetalol hydrochloride, the active form of labetalol, is a white, crystalline compound with a melting point of 200 °C. It is soluble in water and has an acidic pH of 2. Labetalol hydrochloride is synthesized by reacting methylbenzene with labetalol, which forms intermediates such as methyl 4-hydroxylbenzoate and methyl 3-hydroxylbenzoate in the process. The intermediates are then recrystallized to form the final product. Labetalol hydrochloride undergoes thermal analysis using thermogravimetry, calorimetry, and residue analysis to determine its purity. This product also undergoes carbonaceous and oxidative analysis by GC-MS for quality control purposes.

Chemical properties

• Molecular weight: 151.16 g/mol
• Formula: C₈H₉NO₂
• Purity: Min. 95%
• Color/Form: Powder
• InChI: InChI=1S/C8H9NO2/c1-5-2-3-7(10)6(4-5)8(9)11/h2-4,10H,1H3,(H2,9,11)
• InChI key: InChIKey=YNAXKCRTFJQYDT-UHFFFAOYSA-N
• SMILES: Cc1ccc(O)c(C(N)=O)c1