Product Information
- 1-Indone
- 1-Oxobenzocyclopentane
- 1H-Indan-1-one
- 1H-Inden-1-one, 2,3-dihydro-
- 2,3-Dihydro-1-indenone
- 2,3-Dihydro-1H-inden-1-one
- 2,3-Dihydroinden-1-One
- A-Hydrindone
- Alpha-Hydrindon
- I-Indanone
- See more synonyms
- IDO
- Indan-1-Ona
- Indan-1-on
- Indan-1-one
- Indane-1-One
- Indanone
- Nsc 2581
- α-Indanone
1-Indanone is a low potency, irreversible inhibitor of NADH-dependent IDO1 that may be useful as an anti-cancer agent. 1-Indanone inhibits the enzyme IDO1 by steric interactions and pyrazinoic acid. This inhibitor has been shown to have cox-2 inhibitory activity in an experimental model system. In addition, 1-indanone also inhibits mitochondrial membrane potential and can be used as a natriuretic agent. The protein target of 1-indanone is unknown at this time, but it has been shown to inhibit sugar transport in animal models.
Chemical properties
Technical inquiry about: 3D-FI00120 1-Indanone
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