Product Information
- 2-Hydroxyindan2,3-Dihydro-1H-inden-2-ol
- 1H-Inden-2-ol, 2,3-dihydro-
- 2,3-dihydro-,1H-inden-2-ol
- 2-Hydroxyhydrindene
- 2-Hydroxyindan
- 2-Hydroxyindane
- Hydroxyindan,99%
- NSC 17485
2-Indanol is a hydroxy compound that has a human immunodeficiency virus (HIV) replication inhibitor, antiviral activity, and structural formula. It has been shown to have anti-HIV activity in vitro at concentrations of 0.1 μM and 1 μM. 2-Indanol inhibits the process of reverse transcription by specifically binding to the hydroxyl group of the viral RNA polymerase and preventing it from making a hydrogen bond with the viral DNA template strand. 2-Indanol also slows down HIV replication by inhibiting protein synthesis. This inhibition is due to its ability to inhibit phosphorylation and dephosphorylation reactions in the host cell's ribosome machinery, which are required for protein synthesis. 2-Indanol has been shown to be active against covid-19 pandemic influenza viruses and has been used as an antiviral agent in mice infected with these viruses.
Chemical properties
Technical inquiry about: 3D-FI05489 2-Indanol
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