Z-Ile-Glu(OtBu)-Ala-Leu-aldehyde
CAS: 158442-41-2
Ref. 3D-FI111570
| 2mg | 200.00 € | ||
| 5mg | 373.00 € | ||
| 10mg | 578.00 € | ||
| 25mg | 1,035.00 € | ||
| 50mg | 1,801.00 € |
Product Information
- PSI
- Proteasome Inhibitor I
Z-Ile-Glu(OtBu)-Ala-Leu-aldehyde, also known as ZILEAL, is a potent immunosuppressant that binds to the Toll-like receptor (TLR) and inhibits NF-κB binding activity. It has been shown to reduce the activation of macrophages by inhibiting the production of proinflammatory cytokines such as tumor necrosis factor alpha (TNFα), IL-1β, and IL-6. This drug has been shown to inhibit HIV replication in vitro and was also found to have an antiviral effect against herpes simplex virus type 1 in vivo. ZILEAL also inhibits dsDNA binding activity, which may have potential applications in cancer treatment.
Chemical properties
Technical inquiry about: 3D-FI111570 Z-Ile-Glu(OtBu)-Ala-Leu-aldehyde
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