3-Iodo-L-tyrosine

CAS: 70-78-0

Ref. 3D-FI12110

Product Information

• Name: 3-Iodo-L-tyrosine
• Synonyms: (2S)-2-Amino-3-(4-hydroxy-3-iodophenyl)propanoic acid, 3-Iodo-4-hydroxyphenylalanine, 3-Iodo-<span class="text-smallcaps">L</span>-tyrosine, 3-Iodo-D-Tyrosine, 3-Iodo-Tyrosine, 3-Iodotyrosine, 3-Monoiodo-L-Tyrosine, 4-Hydroxy-3-iodophenylalanine, <span class="text-smallcaps">L</span>-Tyrosine, 3-iodo-, H-3-I-Phe(4-Oh)-Oh, H-3-I-Tyr-Oh, H-3-Iodo-Tyr-Oh, H-L-Tyr(3-I)-Oh, H-Tyr(3-I)-Oh, H-Tyr(M-I)-Oh, Iodotyrosine, L-Tyrosine, 3-Iodo-, MIT (amino acid), NSC 210787, Tyrosine, 3-iodo-, <span class="text-smallcaps">L</span>-, Tyrosine,3-Iodo-, L-, MIT

Description

3-Iodo-L-tyrosine is an analog of tyrosine, which has been shown to bind to the thyroid hormone receptor sites. 3-Iodo-L-tyrosine can be used for the diagnosis of thyroid conditions, such as thyroid neoplasms, hyperthyroidism and hypothyroidism. The optimum concentration for 3-iodo-l-tyrosine is between 0.05 and 10 micromolar. 3-Iodo-L-tyrosine can be detected in human serum by a chemical biology method that uses a polymerase chain reaction (PCR) and mass spectroscopy. The principle behind this technique is that 3-iodo-L-tyrosine will bind to monoisotopic tyrosine residues on DNA or RNA molecules, which can be identified using a mass spectrometer. This technique is also able to measure the concentrations of monoiodotyrosine in a sample.

• Brand: Biosynth

Chemical properties

• Molecular weight: 307.09 g/mol
• Formula: C₉H₁₀INO₃
• Purity: Min. 96.0 Area-%
• Color/Form: Powder