Product Information
- 1,3-Dihydro-2H-indol-2-one
- 1,3-Dihydroindol-2-one
- 1,3-dihydro-2H-indol-2-one
- 2,3-Dihidroindol-2-Ona
- 2,3-Dihydro-1H-indol-2-one
- 2,3-Dihydroindol-2-One
- 2,3-Dihydroindol-2-on
- 2,3-Dihydroindole-2-One
- 2-Indolinone
- 2-Oxindole
- See more synonyms
- 2-Oxo-2,3-dihydroindole
- 2-Oxoindole
- 2-Oxoindoline
- 2H-Indol-2-one, 1,3-dihydro-
- Indol-2(3H)-one
- Indolin-2-one
- Indoline-2-one
- Nsc 274863
- O-(Aminophenyl)Acetic acid Lactam
- Oxidinole (Indolin-2-One)
- Oxindol
- Timtec-Bb Sbb004215
- Oxindole
2-Indolone is a synthetic compound that belongs to the class of heterocyclic compounds. It is a trifluoroacetic acid derivative that has been shown to have potent antitumor activity, and it also inhibits cell proliferation. 2-Indolone has been shown to be an effective treatment for inflammatory diseases such as rheumatoid arthritis and Crohn's disease. This compound has been shown to bind to response elements in the promoter region of genes in the basic fibroblast line, and this binding leads to increased expression of gene products involved in inflammation and tumor suppression. The reaction mechanism for 2-indolone involves a two-step process, with activation energies for both steps being high. The first step involves protonation of the C2 hydroxyl group by trifluoroacetic acid, which leads to its displacement by hydrogen from water molecule H2O. In the second step, the oxindole ring opens up, with displacement of
Chemical properties
Technical inquiry about: 3D-FI24580 2-Indolone
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