3-Isobutyl-1-methylxanthine

CAS: 28822-58-4

Ref. 3D-FI24659

Product Information

• Name: 3-Isobutyl-1-methylxanthine
• Synonyms: 3,9-Dihydro-1-methyl-3-(2-methylpropyl)-1H-purine-2,6-dioneIBMX1-Methyl-3-isobutylxanthine
• Brand: Biosynth
• Description: A non-specific inhibitor of cAMP and cGMP phosphodiesterases (PDEs) with IC50 values between 2 and 50 µM. 2-isobutyl-1-methylxanthine (IBMX) has also been found to inhibit phenylephrine-induced 5-HT release by neuroendocrine epithelial cells and IBMX-mediated increase in cAMP and upregulation of Ca2+ channels promotes neuronal differentiation. Additionally IBMX stimulates secretion of thyroid hormones, resulting in cAMP-mediated activation of glycogenolysis and reduced glycogen storage.

Chemical properties

• Molecular weight: 222.24 g/mol
• Formula: C₁₀H₁₄N₄O₂
• Color/Form: Slightly Yellow Powder
• InChI: InChI=1S/C10H14N4O2/c1-6(2)4-14-8-7(11-5-12-8)9(15)13(3)10(14)16/h5-6H,4H2,1-3H3,(H,11,12)
• InChI key: InChIKey=APIXJSLKIYYUKG-UHFFFAOYSA-N
• SMILES: CC(C)Cn1c(=O)n(C)c(=O)c2[nH]cnc21