Isoxepac

CAS: 55453-87-7

Ref. 3D-FI24735

Product Information

• Name: Isoxepac
• Synonyms: 6,11-Dihydro-11-oxo-dibenz[b,e]oxepin-2-acetic acidArtil11-Oxo-6,11-dihydrodibenz[b,e]oxepin-2-acetic acid, (11-Oxo-6,11-Dihydrodibenzo[B,E]Oxepin-2-Yl)Acetic Acid, 11-Oxo-6,11-dihydrobenz(b,e)oxepin-2-acetic acid, 11-Oxo-6,11-dihydrodibenz[b,e]oxepin-2-acetic acid, 11-Oxo-6,11-dihydrodibenzo[b,e]oxepin-2-acetic acid, 2-(11-Oxo-6H-benzo[c][1]benzoxepin-2-yl)acetic acid, 2-(11-oxo-6H-benzo[c][2]benzoxepin-2-yl)acetic acid, 6,11-Dihydro-11-Oxo-Dibenz[B,E]Oxepin-2-Acetic Acid, 6,11-Dihydro-11-oxodibenz[b,e]oxepin-2-acetic acid, Artil, Dibenz[b,e]oxepin-2-acetic acid, 6,11-dihydro-11-oxo-, Hp 549, NSC 300907, P 720549

Description

Isoxepac is a glucuronide conjugate that is an antimicrobial agent. Its side-effect profiles are not well understood, but it has been shown to be eliminated from the body by metabolism. A vivo model has been used to study the pharmacokinetics of this drug. Isoxepac is a prodrug that is metabolized in vivo to its active form, oxepac. Isoxepac has been shown to inhibit growth factor and metabolic disorders by affecting the production of reactive oxygen species and nitric oxide. It also prevents the formation of advanced glycation end products (AGEs) by reacting with dicarbonyl compounds such as methylglyoxal and glyoxal. The hydrochloride salt of Isoxepac has been used in pharmaceutical preparations for topical application.

• Brand: Biosynth

Chemical properties

• Molecular weight: 268.26 g/mol
• Formula: C₁₆H₁₂O₄
• Purity: Min. 95%
• Color/Form: Powder
• InChI: InChI=1S/C16H12O4/c17-15(18)8-10-5-6-14-13(7-10)16(19)12-4-2-1-3-11(12)9-20-14/h1-7H,8-9H2,(H,17,18)
• InChI key: InChIKey=QFGMXJOBTNZHEL-UHFFFAOYSA-N
• SMILES: O=C(O)Cc1ccc2c(c1)C(=O)c1ccccc1CO2