Indole-3-pyruvic acid

CAS: 392-12-1

Ref. 3D-FI30479

Product Information

• Name: Indole-3-pyruvic acid
• Synonyms: 3-(3-Indolyl)-2-oxopropanoic acid, 1H-Indole-3-propanoic acid, α-oxo-, 1H-Indole-3-pyruvic acid, 3-(1H-indol-3-yl)-2-oxopropanoate, 3-(1H-indol-3-yl)-2-oxopropanoic acid, 3-(3-Indolyl)-2-Oxopropanoic Acid, 3-(3-Indolyl)pyruvic acid, 3-Indolylpyroracemic acid, 3-Indolylpyruvic acid, 5-Iodophthalide, Indole-3-(2-Oxo)-Propanoic Acid, Indole-3-Pyruvic Acid Monohydrate, Indole-3-pyruvate, Indolepyruvic acid, Indolyl-3-pyruvate, NSC 88874, Pol 240, alpha-Oxo-1H-indole-3-propanoic acid, α-Oxo-1H-indole-3-propanoic acid, β-Indolepyruvic acid, β-Indolylpyruvic acid

Description

Thiostrepton is an antibiotic that inhibits the synthesis of proteins by binding to the α subunit of the bacterial ribosome. It also has a polymerase chain reaction (PCR) amplification activity. Thiostrepton's inhibitory effect on protein synthesis is due to its ability to bind to the α subunit of the ribosome, which results in inhibition of enzyme activities and physiological function. The thiostrepton-resistant mutants have been found in skin cells and plants. The resistant mutants are mostly due to point mutations in amino acid residues on the surface of the ribosomal target site, which alters its affinity for thiostrepton. This antibiotic has been shown to be active against wild-type strains of bacteria, as well as methicillin-resistant Staphylococcus aureus (MRSA). Thiostrepton's active form is metabolized through hydroxylation and conjugation with glutathione or glucur

• Brand: Biosynth

Chemical properties

• Molecular weight: 203.20 g/mol
• Formula: C₁₁H₉NO₃
• Purity: Area-% Min. 95 Area-%
• Color/Form: Off-White Yellow Powder