Isoalantolactone
CAS: 470-17-7
Ref. 3D-FI32778
| 1g | 1,036.00 € | ||
| 50mg | 145.00 € | ||
| 100mg | 212.00 € | ||
| 250mg | 356.00 € | ||
| 500mg | 574.00 € |
Product Information
- Isohelenin
- (3Ar,4As,8Ar,9Ar)-8A-Methyl-3,5-Dimethylene-Decahydro-Naphtho[2,3-B]Furan-2-One
- (3aR,4aS,8aR,9aR)-8a-methyl-3,5-dimethylidenedecahydronaphtho[2,3-b]furan-2(3H)-one
- (3aR,4aS,8aR,9aR)-Decahydro-8a-methyl-3,5-bis(methylene)naphtho[2,3-b]furan-2(3H)-one
- 5αH-Eudesma-4(15),11(13)-dien-12,8β-olide
- Eudesma-4(14),11(13)-dien-12-oic acid, 8β-hydroxy-, γ-lactone
- Isoallantolactone
- NSC 241036
- Naphtho[2,3-b]furan-2(3H)-one, decahydro-8a-methyl-3,5-bis(methylene)-, (3aR,4aS,8aR,9aR)-
- Naphtho[2,3-b]furan-2(3H)-one, decahydro-8a-methyl-3,5-bis(methylene)-, [3aR-(3aα,4aα,8aβ,9aα)]-
- See more synonyms
Isoalantolactone is a natural compound that has been shown to have pro-apoptotic properties in 3T3-L1 preadipocytes and HL-60 cells. It binds to the dna binding activity of p53, which regulates apoptosis. Isoalantolactone also inhibits NF-κB binding activity and inhibits tubulointerstitial injury in rats with cyclosporin A induced nephropathy. Isoalantolactone can be used as an anti-inflammatory agent, due to its ability to inhibit the activation of NF-κB. The molecular pathogenesis of this drug is not well understood at this time.
Chemical properties
Technical inquiry about: 3D-FI32778 Isoalantolactone
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