Product Information
- 4-Isopropoxyphenylboronic ACID
- 4-ISOPROPOXYBENZENEBORONIC isopropoxybenzeneboronic acid
- Akos Brn-0675
- Chembrdg-Bb 4009733
- P-Isopropoxyphenylboronic ACID
- 4-Isopropoxyphebylboronic acid
- 4-Isopropoxyphenylboronic
- [4-(1-Methylethoxy)Phenyl]Boronic Acid
- 4-iso-Propoxyphenylboronic acid
- 4-Isopropoxybenzeneboronic Acid
- See more synonyms
4-Isopropoxyphenylboronic acid is a boronic acid that can be used as a cross-coupling partner in palladium-catalyzed cross-coupling reactions. It is synthesized by reacting 4-hydroxyphenylacetic acid with 2 equivalents of naphthoquinone diazide. The addition of the 4-isopropoxy group to the phenyl substituent increases the reactivity of this boronic acid. This compound has been used in the synthesis of rofecoxib and cyclooxygenase inhibitors, such as aspirin and ibuprofen. The presence of an electron withdrawing group on one phenyl ring enhances the reactivity of this boronic acid towards nucleophiles, such as amines or alcohols.
Chemical properties
Technical inquiry about: 3D-FI38254 4-Isopropoxyphenylboronic acid
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