(-)-Isoxanthohumol

CAS: 70872-29-6

Ref. 3D-FI45719

Product Information

• Name: (-)-Isoxanthohumol
• Synonyms: (2S)-2,3-Dihydro-7-hydroxy-2-(4-hydroxyphenyl)-5-methoxy-8-(3-methyl-2-buten-1-yl)-4H-1-benzopyran-4-one, (2S)-7,4′-Dihydroxy-5-methoxy-8-(γ,γ-dimethylallyl)flavanone, (2S)-7-Hydroxy-2-(4-hydroxyphenyl)-5-methoxy-8-(3-methylbut-2-enyl)-2,3-dihydrochromen-4-one, 2-Propen-1-one,1-[2,6-dihydroxy-4-methoxy-3-(3-methyl-2-buten-1-yl)phenyl]-3-phenyl-, (2E)-, 2-Propen-1-one,1-[2,6-dihydroxy-4-methoxy-3-(3-methyl-2-butenyl)phenyl]-3-phenyl-, (2E)-, 2-Propen-1-one,1-[2,6-dihydroxy-4-methoxy-3-(3-methyl-2-butenyl)phenyl]-3-phenyl-, (E)-, 4H-1-Benzopyran-4-one, 2,3-dihydro-7-hydroxy-2-(4-hydroxyphenyl)-5-methoxy-8-(3-methyl-2-buten-1-yl)-, (2S)-, 4H-1-Benzopyran-4-one, 2,3-dihydro-7-hydroxy-2-(4-hydroxyphenyl)-5-methoxy-8-(3-methyl-2-butenyl)-, (2S)-, 4H-1-Benzopyran-4-one, 2,3-dihydro-7-hydroxy-2-(4-hydroxyphenyl)-5-methoxy-8-(3-methyl-2-butenyl)-, (S)-, Isoxanthohumol (Helichrysum), Isoxanthohumol (Sophora)
• CAS: 70872-29-6

Description

(-)-Isoxanthohumol is a natural compound found in hops that has biological properties, such as anti-inflammatory activity and antimicrobial effects. It is used as a chromatographic method for the analysis of chlorogenic acids, which are found in plants. (-)-Isoxanthohumol is also an inhibitor of toll-like receptor 4 (TLR4) signaling and genotoxic activity. It inhibits the production of inflammatory cytokines and chemokines by inhibiting TLR4 signaling pathways. This compound can be used as an analytical tool to investigate the matrix effect in high-performance liquid chromatography (HPLC).

• Brand: Biosynth

Chemical properties

• Molecular weight: 354.4 g/mol
• Formula: C₂₁H₂₂O₅
• Purity: Min. 95%
• Color/Form: Powder
• InChI: InChI=1S/C21H22O5/c1-12(2)4-9-15-16(23)10-19(25-3)20-17(24)11-18(26-21(15)20)13-5-7-14(22)8-6-13/h4-8,10,18,22-23H,9,11H2,1-3H3
• InChI key: InChIKey=YKGCBLWILMDSAV-UHFFFAOYSA-N
• SMILES: COc1cc(O)c(CC=C(C)C)c2c1C(=O)CC(c1ccc(O)cc1)O2