Product Information
Name:5-Iodoisatin
Synonyms:
- 5-Iodoindole-2,3-dione5-Iodo-2,3-indolinedione
Brand:Biosynth
Description:5-Iodoisatin is a cross-coupling agent that has an inhibitory effect on tumor tissue. It is also used for the synthesis of conjugated drugs and pharmacological research. 5-Iodoisatin, which forms a ternary complex with copper and iodide, inhibits the growth of colorectal carcinoma cells by interfering with their DNA replication and protein production. 5-Iodoisatin can be converted to its active form through the formation of a ternary complex with copper and iodide ions. This inhibition is due to its ability to interact with DNA, RNA polymerase, and other proteins involved in transcription, translation, and replication processes. 5-Iodoisatin is metabolized through conjugation with glucuronic acid or sulfate in the liver; it binds to human mitochondrial DNA and can enter cells via passive diffusion. The carbonyl group in this drug may play an important role in its interaction with cancer cells.
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Chemical properties
Molecular weight:273.03 g/mol
Formula:C8H4INO2
Purity:Min. 95%
Technical inquiry about: 5-Iodoisatin
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