Isocorydine

CAS: 475-67-2

Ref. 3D-FI66638

Product Information

• Name: Isocorydine
• Synonyms: Luteanine, (+)-Isocorynoline, (6aS)-1,2,10-trimethoxy-6-methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinolin-11-ol, (6aS)-5,6,6a,7-Tetrahydro-1,2,10-trimethoxy-6-methyl-4H-dibenzo[de,g]quinolin-11-ol, 1,2,10-trimethoxy-6-methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinolin-11-ol, 4H-Dibenzo(de,g)quinolin-11-ol, 5,6,6a,7-tetrahydro-1,2,10-trimethoxy-6-methyl-, (S)-, 4H-Dibenzo[de,g]quinolin-11-ol, 5,6,6a,7-tetrahydro-1,2,10-trimethoxy-6-methyl-, (6aS)-, 6a-alpha-Aporphin-11-ol, 1,2,10-trimethoxy-, 6aalpha-Aporphin-11-ol, 1,2,10-trimethoxy-, 6aα-Aporphin-11-ol, 1,2,10-trimethoxy-, <span class="text-smallcaps">L</span>-(+)-Isocorydine, Aporphin-11-ol, 1,2,10-trimethoxy-, Artabotrin, Artabotrine, Brn 0094792, L-(+)-Isocorydine, Lindcarpine, N,O-dimethyl-, Luteanin, Luteanine (VAN), Luteanine (aporphine), Nsc 32979, Nsc 645316, S-(+)-Isocorydine, Uzokoridin, d-Isocorydine

Description

Isocorydine is a bisbenzylisoquinoline alkaloid that has been shown to have cytotoxic effects on murine hepatoma cells. Isocorydine binds to the protopine site of the enzyme papillary muscle, inhibiting DNA synthesis and cell division. It also inhibits the growth of human carcinoma cells (HL-60) by binding to their DNA and inhibiting RNA synthesis. Isocorydine has been shown to inhibit the production of interleukin-1β (IL-1β), which may contribute to its anti-inflammatory properties.
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Isocorydine is a bisbenzylisoquinoline alkaloid that has been shown to have cytotoxic effects on murine hepatoma cells. Isocorydine binds to the protopine site of the enzyme papillary muscle, inhibiting DNA synthesis and cell division. It also inhibits the growth

• Brand: Biosynth

Chemical properties

• Molecular weight: 341.4 g/mol
• Formula: C₂₀H₂₃NO₄
• Purity: Min. 95%
• Color/Form: White Powder
• InChI: InChI=1S/C20H23NO4/c1-21-8-7-12-10-15(24-3)20(25-4)18-16(12)13(21)9-11-5-6-14(23-2)19(22)17(11)18/h5-6,10,13,22H,7-9H2,1-4H3/t13-/m0/s1
• InChI key: InChIKey=QELDJEKNFOQJOY-ZDUSSCGKSA-N
• SMILES: COc1ccc2c(c1O)-c1c(OC)c(OC)cc3c1[C@H](C2)N(C)CC3