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Isotetrandrine
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Isotetrandrine

CAS: 477-57-6

Ref. 3D-FI71710

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Estimated delivery in United States, on Tuesday 18 Feb 2025

Product Information

Name:
Isotetrandrine
Synonyms:
  • 2-Methylberbamine
  • (1Beta,1'Beta)-6,6',7,12-Tetramethoxy-2,2'-Dimethylberbaman
  • (4aS,16aR)-3,4,4a,5,16a,17,18,19-Octahydro-12,21,22,26-tetramethoxy-4,17-dimethyl-16H-1,24:6,9-dietheno-11,15-metheno-2H-pyrido[2′,3′:17,18][1,11]dioxacycloeicosino[2,3,4-ij]isoquinoline
  • (R,S)-Tetrandrine
  • 1-Isotetrandrine
  • 16H-1,24:6,9-Dietheno-11,15-metheno-2H-pyrido[2′,3′:17,18][1,11]dioxacycloeicosino[2,3,4-ij]isoquinoline, 3,4,4a,5,16a,17,18,19-octahydro-12,21,22,26-tetramethoxy-4,17-dimethyl-, (4aS,16aR)-
  • 16H-1,24:6,9-Dietheno-11,15-metheno-2H-pyrido[2′,3′:17,18][1,11]dioxacycloeicosino[2,3,4-ij]isoquinoline, 3,4,4a,5,16a,17,18,19-octahydro-12,21,22,26-tetramethoxy-4,17-dimethyl-, [4aS-(4aR*,16aS*)]-
  • 6,6',7,12-Tetramethoxy-2,2'-dimethylberbaman
  • 8,19,20,25-Tetramethoxy-14,30-Dimethyl-6,22-Dioxa-14,30-Diazaheptacyclo[22.6.2.2~2,5~.1~7,11~.1~13,17~.0~21,33~.0~27,31~]Hexatriaconta-2,4,7(34),8,10,17(33),18,20,24,26,31,35-Dodecaene (Non-Preferred Name)
  • Berbaman, 6,6',7,12-tetramethoxy-2,2'-dimethyl- (9CI)
  • See more synonyms
  • Berbaman, 6,6′,7,12-tetramethoxy-2,2′-dimethyl-
  • Ccris 6540
  • Isosinomenin A
  • Isosinomenine A
  • Nsc 97338
  • O,O'-Dimethylobamegine
  • O,O'-Dimethylstepholine
  • O-Methylberbamine
Description:

Isotetrandrine is a natural compound that inhibits the production of reactive oxygen species and protects cells against oxidative injury. Isotetrandrine has been shown to have anti-inflammatory properties, which may be due to its inhibition of prostaglandin synthesis. It also has hypoglycemic effects in diabetic mice, with a significant reduction in blood glucose levels and increased insulin sensitivity. The apoptotic effect of isotetrandrine has been observed in HL-60 cells, which is mediated by the mitochondrial pathway. This compound also has genotoxic activity that can lead to cancerous transformation. Isotetrandrine can be synthesized from tetrandrine, an alkaloid found in plants of the genus Papaveraceae.

Notice:
Our products are intended for lab use only. For any other use, please contact us.
Brand:
Biosynth
Long term storage:
Notes:

Chemical properties

Molecular weight:
622.75 g/mol
Formula:
C38H42N2O6
Purity:
Min. 95%
MDL:
Melting point:
Boiling point:
Flash point:
Density:
Concentration:
EINECS:
Merck:
HS code:

Hazard Info

UN Number:
EQ:
Class:
H Statements:
P Statements:
Forbidden to fly:
Hazard Info:
Packing Group:
LQ:

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