Isobavachalcone

CAS: 20784-50-3

Ref. 3D-FI73915

Product Information

• Name: Isobavachalcone
• Synonyms: (2E)-1-[2,4-Dihydroxy-3-(3-methyl-2-butenyl)phenyl]-3-(4-hydroxyphenyl)-2-propen-1-one, 2-Propen-1-one, 1-[2,4-dihydroxy-3-(3-methyl-2-butenyl)phenyl]-3-(4-hydroxyphenyl)-, (2E)-, 2-Propen-1-one, 1-[2,4-dihydroxy-3-(3-methyl-2-butenyl)phenyl]-3-(4-hydroxyphenyl)-, (E)-, 2-propen-1-one, 1-[2,4-dihydroxy-3-(3-methyl-2-buten-1-yl)phenyl]-3-(4-hydroxyphenyl)-, (2E)-, 4-Hydroxyisocordoin, Chalcone, 2′,4,4′-trihydroxy-3′-(3-methyl-2-butenyl)-, Corylifolinin, Isobacachalcone, iso-Bavachalcone

Description

Isobavachalcone is a natural compound that belongs to the group of flavonoids. It has been shown to be cytotoxic at high concentrations (e.g., 50 μM) in HL-60 cells and induce apoptosis by increasing the expression of pro-apoptotic proteins. Isobavachalcone also has anti-inflammatory properties, which may be due to its ability to inhibit the production of reactive oxygen species and increase the expression of nuclear DNA binding protein DDB2. Isobavachalcone can be used as an analytical tool for determining mitochondrial membrane potential and for identifying compounds with autophagic activity.

• Brand: Biosynth

Chemical properties

• Molecular weight: 324.37 g/mol
• Formula: C₂₀H₂₀O₄
• Purity: Min. 98 Area-%
• InChI: InChI=1S/C20H20O4/c1-13(2)3-9-16-19(23)12-10-17(20(16)24)18(22)11-6-14-4-7-15(21)8-5-14/h3-8,10-12,21,23-24H,9H2,1-2H3/b11-6+
• InChI key: InChIKey=DUWPGRAKHMEPCM-IZZDOVSWSA-N
• SMILES: CC(C)=CCc1c(O)ccc(C(=O)/C=C/c2ccc(O)cc2)c1O