Isoastragaloside I
CAS: 84676-88-0
Ref. 3D-FI74369
| 1mg | 144.00 € | ||
| 2mg | 189.00 € | ||
| 5mg | 352.00 € | ||
| 10mg | 542.00 € | ||
| 25mg | 1,033.00 € |
Product Information
- astragalosideⅠ
- (3beta,6alpha,16beta,20R,24S)-3-[(2,4-Di-O-acetyl-beta-D-xylopyranosyl)oxy]-20,24-epoxy-16,25-dihydroxy-9,19-cyclolanostan-6-yl beta-D-glucopyranoside
Isoastragaloside I is a natural compound that is extracted from the Chinese herb, Isatis indigotica. It has shown to have anti-inflammatory activity in vitro and in vivo, and may be a potential therapeutic agent for inflammatory bowel disease. Isoastragaloside I inhibits the activation of toll-like receptor 4 (TLR4) which can stimulate inflammation. This inhibition may be due to its ability to suppress TLR4-mediated activation of nuclear factor kappa B (NFκB) and subsequent production of proinflammatory cytokines such as tumor necrosis factor α (TNFα). The cytotoxicity of isoaistragaloside I was evaluated using bovine fetal liver cells. It showed no toxicity on cells at concentrations up to 1000 μM, demonstrating that it is safe for use in vivo.
Chemical properties
Technical inquiry about: 3D-FI74369 Isoastragaloside I
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