Product Information
- 4H-1-Benzopyran-4-one, 5,7-dihydroxy-3-(4-hydroxy-3-methoxyphenyl)-6-methoxy-
- 5,7-Dihydroxy-3-(4-hydroxy-3-methoxyphenyl)-6-methoxy-4H-1-benzopyran-4-one
Iristectorigenin A is a natural compound that is obtained from the Chinese herb, I. sinensis. Iristectorigenin A has been shown to inhibit the proliferation of human promyelocytic leukemia cells (HL-60) by blocking angiogenesis. It also has anti-inflammatory properties, which may be due to its ability to inhibit the production of inflammatory cytokines and prostaglandins. The IC50 for ristectorigenin A was found to be 0.5 μM in human serum and 2 μM in human epidermal growth factor. The fatty acid extract of ristectorigenin A showed an IC50 of 1 μM in trifluoroacetic acid and acetate extract with a value of 10 μM in fetal bovine serum at pH 8.5 and 37°C for polymerase chain reaction (PCR) amplification.
Chemical properties
Technical inquiry about: 3D-FI74508 Iristectorigenin A
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