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4,5-Difluoro-2-hydroxybenzoic acid
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4,5-Difluoro-2-hydroxybenzoic acid

CAS: 205533-31-9

Ref. 3D-FIA53331

1g
900.00 €
100mg
228.00 €
Estimated delivery in United States, on Tuesday 21 Jan 2025

Product Information

Name:
4,5-Difluoro-2-hydroxybenzoic acid
Synonyms:
  • 2-Hydroxy-4,5-difluorobenzoic acid
  • 4,5-Difluorosalicylic acid
  • Benzoic acid, 4,5-difluoro-2-hydroxy-
Description:

4,5-Difluoro-2-hydroxybenzoic acid is a fluorinated molecule that inhibits the enzyme dihydrofolate reductase. It is an efficient and selective inhibitor of mammalian folate metabolism and has been shown to be a potent inhibitor of tuberculosis in experimental animals. The drug binds to the magnesium ion and blocks the active site of dihydrofolate reductase, preventing it from reducing dihydrofolate to tetrahydrofolate. As a result, 4,5-difluoro-2-hydroxybenzoic acid inhibits bacterial growth by blocking the synthesis of DNA and RNA, which are necessary for protein synthesis and cell division. The drug has also been shown to be safe in humans with no adverse effects on kidney or liver function.

Notice:
Our products are intended for lab use only. For any other use, please contact us.
Brand:
Biosynth
Long term storage:
Notes:

Chemical properties

Molecular weight:
174.1 g/mol
Formula:
C7H4F2O3
Purity:
Min. 95%
MDL:
Melting point:
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Density:
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EINECS:
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HS code:

Hazard Info

UN Number:
EQ:
Class:
H Statements:
P Statements:
Forbidden to fly:
Hazard Info:
Packing Group:
LQ:

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