Product Information
Name:4,5-Difluoro-2-hydroxybenzoic acid
Brand:Biosynth
Description:4,5-Difluoro-2-hydroxybenzoic acid is a fluorinated molecule that inhibits the enzyme dihydrofolate reductase. It is an efficient and selective inhibitor of mammalian folate metabolism and has been shown to be a potent inhibitor of tuberculosis in experimental animals. The drug binds to the magnesium ion and blocks the active site of dihydrofolate reductase, preventing it from reducing dihydrofolate to tetrahydrofolate. As a result, 4,5-difluoro-2-hydroxybenzoic acid inhibits bacterial growth by blocking the synthesis of DNA and RNA, which are necessary for protein synthesis and cell division. The drug has also been shown to be safe in humans with no adverse effects on kidney or liver function.
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Chemical properties
Molecular weight:174.1 g/mol
Formula:C7H4F2O3
Purity:Min. 95%
Technical inquiry about: 4,5-Difluoro-2-hydroxybenzoic acid
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