Product Information
Name:Kemptide trifluoroacetate salt
Synonyms:
- H-Leu-Arg-Arg-Ala-Ser-Leu-Gly-OH H-LRRASLG-OH
Brand:Biosynth
Description:Kemptide is a substrate molecule that has been shown to inhibit the enzyme activity of some protein kinases. Kemptide is a 3-amino acid peptide that contains the amino acids L-leucine, L-arginine, and L-arginine. It was originally isolated from an extract of human brain tissue and has been shown to inhibit the activity of protein kinase C (PKC), phosphorylase kinase, and glycogen synthase kinase 3β in vitro assays. Kemptide also inhibits the expression of genes encoding PKCα1, PKCα2, PKCδ, PKCε, PKCγ1, PKCγ2, PKCζ in t84 cells. The inhibition of these genes suggests that kemptide may be useful as a drug candidate for inhibiting protein kinases in vivo.
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Chemical properties
Molecular weight:771.91 g/mol
Formula:C32H61N13O9·xC2HF3O2
Purity:Min. 95%
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