Kartogenin

CAS: 4727-31-5

Ref. 3D-FK164842

Product Information

• Name: Kartogenin
• CAS: 4727-31-5

Description

Kartogenin is a naturally occurring glycosaminoglycan that is associated with cartilage tissue. It has been shown to be up-regulated in response to growth factors, including growth factor-β1. Kartogenin may also have a role in the regulation of gene transcription and the development of inflammatory processes. The molecule has been shown to inhibit proinflammatory cytokines (e.g., IL-1β, IL-6) and stimulate production of anti-inflammatory cytokine IL-10. Cartilage tissue from patients with osteoarthritis has significantly lower levels of kartogenin than healthy tissues, which may account for the increased levels of inflammation in these patients.

• Brand: Biosynth

Chemical properties

• Molecular weight: 317.34 g/mol
• Formula: C₂₀H₁₅NO₃
• Purity: Min. 95%
• InChI: InChI=1S/C20H15NO3/c22-19(17-8-4-5-9-18(17)20(23)24)21-16-12-10-15(11-13-16)14-6-2-1-3-7-14/h1-13H,(H,21,22)(H,23,24)
• InChI key: InChIKey=SLUINPGXGFUMLL-UHFFFAOYSA-N
• SMILES: O=C(O)c1ccccc1C(=O)Nc1ccc(-c2ccccc2)cc1