CAS 4727-31-5

Kartogenin

Description:

Kartogenin is a small organic molecule that has garnered attention for its potential therapeutic applications, particularly in cartilage regeneration and repair. It is classified as a synthetic compound and is known for its ability to promote chondrogenesis, the process by which cartilage is formed. Kartogenin functions by modulating specific signaling pathways, notably enhancing the differentiation of mesenchymal stem cells into chondrocytes, which are the cells responsible for cartilage formation. This characteristic makes it a candidate for treating osteoarthritis and other degenerative joint diseases. In terms of its chemical structure, Kartogenin features a unique arrangement of functional groups that contribute to its biological activity. The compound is typically studied in the context of its pharmacological effects, including its anti-inflammatory properties and its role in promoting tissue repair. As research continues, Kartogenin may offer insights into novel therapeutic strategies for musculoskeletal disorders. However, further studies are necessary to fully understand its mechanisms of action and potential side effects.

Formula: C20H15NO3

InChI: InChI=1S/C20H15NO3/c22-19(17-8-4-5-9-18(17)20(23)24)21-16-12-10-15(11-13-16)14-6-2-1-3-7-14/h1-13H,(H,21,22)(H,23,24)

InChI key: SLUINPGXGFUMLL-UHFFFAOYSA-N

SMILES: C1=CC=C(C=C1)C2=CC=C(C=C2)NC(=O)C3=CC=CC=C3C(=O)O

Kartogenin

CAS: 4727-31-5

Formula: C₂₀H₁₅NO₃

Purity: >98.0%(HPLC)(T)

Color and Shape: White to Light yellow powder to crystal

Molecular weight: 317.34

Ref: 3B-K0078

n-Biphenyl-4-yl-phthalamic acid

CAS: 4727-31-5

n-Biphenyl-4-yl-phthalamic acid

Formula: C₂₀H₁₅NO₃

Purity: 98%

Color and Shape: Solid

Molecular weight: 317.338

Ref: 54-OR323094

Kartogenin

CAS: 4727-31-5

Kartogenin

Formula: C₂₀H₁₅NO₃

Purity: ≥95%

Molecular weight: 317.34

Ref: 54-BUP09707

2-[([1,1'-Biphenyl]-4-ylamino)carbonyl]benzoic acid

CAS: 4727-31-5

Formula: C₂₀H₁₅NO₃

Purity: 98%

Color and Shape: Solid

Molecular weight: 317.3380

Ref: IN-DA003EOM

Kartogenin

Controlled Product

CAS: 4727-31-5

Applications Kartogenin is a potent, selective, and non-cytotoxic downstream RUNX1 and RUNX2 modulator. Kartogenin causes mesenchymal stem cells found in joints to differentiate into chondrocyte cells that can build cartilage where it has been destroyed.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Ruschig, H., et al.: Arzneim.-Forsch. Drug Res., 23, 1745 (1973), Hartmann, R., et al.: J. Med. Chem., 35, 2210 (1992), Kishida., et al.: Biochemistry, 45, 783 (2006), Chem. and Eng. News 90, 34 (2012)

Formula: C₂₀H₁₅NO₃

Color and Shape: Neat

Molecular weight: 317.34

Ref: TR-K139800

Kartogenin

CAS: 4727-31-5

Kartogenin (KGN) is an activator of the smad4/smad5 pathway, and promotes the selective differentiation of multipotent mesenchymal stem cells into chondrocytes.

Formula: C₂₀H₁₅NO₃

Purity: 96.25% - 98.85%

Color and Shape: White Solid

Molecular weight: 317.338

Ref: TM-T1748

Kartogenin

CAS: 4727-31-5

2-([1,1'-Biphenyl]-4-ylcarbamoyl)benzoic acid

Formula: C₂₀H₁₅NO₃

Purity: 98%

Molecular weight: 317.34

Ref: IN-DG247584

2-([1,1'-Biphenyl]-4-ylcarbamoyl)benzoic acid

CAS: 4727-31-5

Formula: C₂₀H₁₅NO₃

Purity: 98%

Color and Shape: Solid

Molecular weight: 317.344

Ref: 10-F320934

Kartogenin-d4

Controlled Product

CAS: 4727-31-5

Applications Labelled Kartogenin (K139800). Kartogenin is a potent, selective, and non-cytotoxic downstream RUNX1 and RUNX2 modulator. Kartogenin causes mesenchymal stem cells found in joints to differentiate into chondrocyte cells that can build cartilage where it has been destroyed.
References Ruschig, H., et al.: Arzneim.-Forsch. Drug Res., 23, 1745 (1973), Hartmann, R., et al.: J. Med. Chem., 35, 2210 (1992), Kishida., et al.: Biochemistry, 45, 783 (2006),

Formula: C₂₀D₄H₁₁NO₃

Color and Shape: Neat

Molecular weight: 321.363

Ref: TR-K139802