DL-Kynurenine, free base

CAS: 343-65-7

Ref. 3D-FK172296

Product Information

• Name: DL-Kynurenine, free base
• Synonyms: 2-Amino-4-(2-Aminophenyl)-4-Oxobutanoic Acid, 2-Amino-4-(2-aminophenyl)-4-oxobutanoicacid, 3-Anthraniloyl-<span class="text-smallcaps">D</smallcap><smallcap>L</span>-alanine, 3-Anthraniloylalanine, <span class="text-smallcaps">DL</span>-Kynurenine, Alanine, 3-anthraniloyl-, Benzenebutanoic acid, α,2-diamino-γ-oxo-, Beta-Anthraniloyl-Alpha-Alanine, Dl-Kynurenine Free Base, Kynurenin, Kynurenine, α,2-Diamino-γ-oxobenzenebutanoic acid

Description

DL-Kynurenine, free base is an amino acid that is a product of the normal catabolic pathway for tryptophan. It is also present in some foods and may be produced endogenously from tryptophan or kynurenine. DL-Kynurenine is used as a polymerase chain reaction (PCR) substrate to detect enterovirus RNA and has been shown to be effective against bowel disease in vitro. DL-Kynurenine has been studied as a potential pharmacological agent for the treatment of inflammatory diseases such as rheumatoid arthritis, Crohn's disease, ulcerative colitis, and psoriasis. DL-Kynurenine binds to toll-like receptor 4 (TLR4) and inhibits picolinic acid production by macrophages. This leads to decreased matrix metalloproteinase activity and energy metabolism, which may have a protective effect on neuronal death by reducing oxidative stress.

• Brand: Biosynth

Chemical properties

• Molecular weight: 208.20 g/mol
• Formula: C₁₀H₁₂N₂O₃
• Purity: Min. 95%