DL-Kynurenine, free base

CAS: 343-65-7

Ref. 3D-FK172296

Product Information

• Name: DL-Kynurenine, free base
• Brand: Biosynth
• Description: DL-Kynurenine, free base is an amino acid that is a product of the normal catabolic pathway for tryptophan. It is also present in some foods and may be produced endogenously from tryptophan or kynurenine. DL-Kynurenine is used as a polymerase chain reaction (PCR) substrate to detect enterovirus RNA and has been shown to be effective against bowel disease in vitro. DL-Kynurenine has been studied as a potential pharmacological agent for the treatment of inflammatory diseases such as rheumatoid arthritis, Crohn's disease, ulcerative colitis, and psoriasis. DL-Kynurenine binds to toll-like receptor 4 (TLR4) and inhibits picolinic acid production by macrophages. This leads to decreased matrix metalloproteinase activity and energy metabolism, which may have a protective effect on neuronal death by reducing oxidative stress.

Chemical properties

• Molecular weight: 208.20 g/mol
• Formula: C₁₀H₁₂N₂O₃
• Purity: Min. 95%