Kebuzone

CAS: 853-34-9

Ref. 3D-FK24754

Product Information

• Name: Kebuzone
• Synonyms: 4-(3-Oxobutyl)-1,2-diphenyl-3,5-pyrazolidinedion, 1,2-Diphenyl-4-(2-acetylethyl)pyrazolidine-3,5-dione, 1,2-Diphenyl-4-(g-ketobutyl)-3,5-pyrazolidinedione, 212-715-7, 3,5-Pyrazolidinedione, 4-(3-oxobutyl)-1,2-diphenyl-, 4-(3-Oxobutyl)-1,2-diphenyl-3,5-pyrazolidinedione, 4-(3-Oxobutyl)-1,2-diphenylpyrazolidine-3,5-dione, 853-34-9, Chebutan, Chepirol, Chetazol, Chetazolidin, Chetil, Chetopir, Copirene, Gammachetone, Ketanol, Ketason, Ketazon, Ketazone, Ketophenylbutazone (JAN), Pecnon, Phloguron, Recheton, Reuchetal, γ-Ketazone, γ-Ketophenylbutazone, γ-Oxophenylbutazone, Ketophenylbutazone

Description

Kebuzone is a non-steroidal anti-inflammatory drug that has been used in the treatment of inflammatory bowel disease. The mechanism of action of Kebuzone is as an inhibitor of 5-lipoxygenase, which is responsible for the production of leukotrienes. Kebuzone also inhibits the activity of other enzymes such as cyclooxygenase and lipoxygenase, which are involved in the production of prostaglandins and other inflammatory mediators. In addition to these effects, Kebuzone has been found to be effective against infectious diseases, including malaria. The drug can be administered orally or intravenously and is excreted unchanged by the kidneys following oral administration. It also undergoes extensive metabolism in humans with a metabolic rate that is higher than that reported for most drugs.

• Brand: Biosynth

Chemical properties

• Molecular weight: 322.36 g/mol
• Formula: C₁₉H₁₈N₂O₃
• Purity: Min. 95%
• Color/Form: Off-White Powder
• InChI: InChI=1S/C19H18N2O3/c1-14(22)12-13-17-18(23)20(15-8-4-2-5-9-15)21(19(17)24)16-10-6-3-7-11-16/h2-11,17H,12-13H2,1H3
• InChI key: InChIKey=LGYTZKPVOAIUKX-UHFFFAOYSA-N
• SMILES: CC(=O)CCC1C(=O)N(c2ccccc2)N(c2ccccc2)C1=O