2-Ketopimelic acid

CAS: 17126-90-8

Ref. 3D-FK65771

Product Information

• Name: 2-Ketopimelic acid
• Synonyms: Heptanedioic acid, 2-oxo-, α-Ketopimelic acid, 2-Oxoheptanedioic acid, 2-Oxopimelic acid, α-Oxopimelic acid

Description

2-Ketopimelic acid is a fatty acid that is produced by the catalysis of 2-ketoglutarate. It is found in the mitochondrial matrix and in the biosynthesis of fatty acids. The wild-type strain of E. coli has been shown to produce 2-ketopimelic acid during aerobic growth on glucose, while mutant strains did not synthesize this compound. The production of 2-ketopimelic acid requires a functional acyl carrier protein (ACP) and an active enoyl reductase (ER). The biosynthesis of 2-ketopimelic acid can be catalysed by dehydrogenase enzymes such as enoyl reductase, which are involved in the conversion of 3-oxoacyl CoA into 3-hydroxyacyl CoA.
2-Ketopimelic acid may also play a role in tuberculosis, as it has been detected in human protein using reaction monitoring techniques

• Brand: Biosynth

Chemical properties

• Molecular weight: 174.15 g/mol
• Formula: C₇H₁₀O₅
• Purity: Min. 95%
• Color/Form: Powder
• InChI: InChI=1S/C7H10O5/c8-5(7(11)12)3-1-2-4-6(9)10/h1-4H2,(H,9,10)(H,11,12)
• InChI key: InChIKey=HABHUTWTLGRDDU-UHFFFAOYSA-N
• SMILES: O=C(O)CCCCC(=O)C(=O)O