L-tert-Leucine

CAS: 20859-02-3

Ref. 3D-FL12004

Product Information

• Name: L-tert-Leucine
• Synonyms: (S)-2-Amino-3,3-dimethylbutyric acidL-a-tert-Butylglycine, (2S)-2-Amino-3,3-dimethylbutanoic acid, (S)-2-Amino-3,3-dimethylbutanoic acid, (S)-2-Amino-3,3-dimethylbutyric acid, (S)-tert-Butylglycine, (S)-tert-Leucine, 2-Amino-3,3-Dimethyl-Butanoic Acid, 3-Methyl-<span class="text-smallcaps">L</span>-valine, 3-Methyl-l-valine, 3-Methylvaline, <span class="text-smallcaps">L</span>-2-Amino-3,3-dimethylbutyric acid, <span class="text-smallcaps">L</span>-Pseudoleucine, <span class="text-smallcaps">L</span>-Valine, 3-methyl-, <span class="text-smallcaps">L</span>-tert-Butylglycine, <span class="text-smallcaps">L</span>-tert-Leucine, Butyric acid, 2-amino-3,3-dimethyl-, <span class="text-smallcaps">L</span>-, D-t-Butylglycine, H-Tle-OH, L-valine,3-methyl, NSC 203785, Nsc203785, tert-<span class="text-smallcaps">L</span>-Leucine, tert-Butyl-<span class="text-smallcaps">L</span>-glycine, β-Methyl-<span class="text-smallcaps">L</span>-valine

Description

L-tert-Leucine is a chiral compound that inhibits the activity of metalloproteases, enzymes that catalyze the breakdown of proteins. L-tert-Leucine has been shown to inhibit proteolytic activity in recombinant cells and bacterial strain such as Escherichia coli, Pseudomonas aeruginosa, and Bacillus subtilis. L-tert-Leucine binds to the active site of metalloproteases by competitive inhibition, inhibiting the breakdown of proteins. This compound also prevents degradation of dinucleotide phosphate and chiral synthesis. The enantiopure form of this compound is used as a substrate for kinetic studies with type strains of various metalloprotease enzymes.

• Brand: Biosynth

Chemical properties

• Molecular weight: 131.17 g/mol
• Formula: C₆H₁₃NO₂
• Purity: (%) Min. 95%
• Color/Form: White Powder
• InChI: InChI=1S/C6H13NO2/c1-6(2,3)4(7)5(8)9/h4H,7H2,1-3H3,(H,8,9)/t4-/m1/s1
• InChI key: InChIKey=NPDBDJFLKKQMCM-SCSAIBSYSA-N
• SMILES: CC(C)(C)[C@H](N)C(=O)O