LCZ696

CAS: 936623-90-4

Ref. 3D-FL137695

Product Information

• Name: LCZ696
• Brand: Biosynth
• Description: Lcz696 is an ester prodrug of the active compound crizotinib, which is a selective inhibitor of the enzyme tyrosine kinase. Lcz696 has been shown to be effective in combination therapy for the treatment of patients with metastatic non-small cell lung cancer and those who are resistant to first-line chemotherapy. This drug has also been shown to have beneficial effects on cardiac function and blood pressure. Lcz696 inhibits MMP-9 activity and reduces levels of natriuretic peptides, which may be due to its inhibition of Toll-like receptor 4 (TLR4).

Chemical properties

• Molecular weight: 1,922.04 g/mol
• Formula: C₂₄H₂₉N₅O₃•C₂₄H₂₉NO₅•(H₂O)₂•Na₃
• Purity: Min. 95%