Product Information
Name:(+/-)-Lisofylline
Controlled Product
Synonyms:
- 3,7-Dihydro-1-(5-hydroxyhexyl)-3,7-dimethyl-1H-purine-2,6-dione
Brand:Biosynth
Description:Lisofylline is a chemical inhibitor of P-glycoprotein (P-gp), which belongs to the group of pharmacological agents. It is used as an active inhibitor in the treatment of bowel disease and is a low potency, non-selective squamous cell nuclear dna (SCCN) p-gp inhibitor. Lisofylline has shown to be an active inhibitor of P-gp in human colon cancer cells. Lisofylline inhibits mitochondrial membrane potential by binding to the rate constant and response element, which prevents ATP production and leads to cell death through oxidative injury.
Notice:Our products are intended for lab use only. For any other use, please contact us.
Chemical properties
Molecular weight:280.32 g/mol
Formula:C13H20N4O3
Purity:Min. 95%
InChI:InChI=1S/C13H20N4O3/c1-9(18)6-4-5-7-17-12(19)10-11(14-8-15(10)2)16(3)13(17)20/h8-9,18H,4-7H2,1-3H3
InChI key:InChIKey=NSMXQKNUPPXBRG-UHFFFAOYSA-N
SMILES:CC(O)CCCCn1c(=O)c2c(ncn2C)n(C)c1=O
Technical inquiry about: (+/-)-Lisofylline
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