Leupeptin hemisulfate

CAS: 103476-89-7

Ref. 3D-FL29627

Product Information

• Name: Leupeptin hemisulfate
• Synonyms: L-Leucinamide, N-acetyl-L-leucyl-N-[(1S)-4-[(aminoiminomethyl)amino]-1-formylbutyl]-, sulfate, (2S)-2-(acetylamino)-N-[(2S)-2-({4-[(diaminomethylidene)amino]-1-formylbutyl}amino)-4-methylpentanoyl]-4-methylpentanamide (non-preferred name), 2-(2-Acetamido-4-methylvaleramido)-N-(1-formyl-4-guanidinobutyl)-4-methylvaleramide, <span class="text-smallcaps">L</smallcap>-Leucinamide, N-acetyl-<smallcap>L</span>-leucyl-N-[(1S)-4-[(aminoiminomethyl)amino]-1-formylbutyl]-, sulfate (2:1), <span class="text-smallcaps">L</smallcap>-Leucinamide, N-acetyl-<smallcap>L</span>-leucyl-N-[4-[(aminoiminomethyl)amino]-1-formylbutyl]-, (S)-, sulfate (2:1), Acetyl-L-leucyl-L-leucylargininal, L-Leucinamide, N-acetyl-L-leucyl-N-(4-((aminoiminomethyl)amino)-1-formylbutyl)-, Leupeptin Ac-LL, Leupeptin Hemisulfate From Microbial*Source, N-Acetyl-L-leucyl-L-leucyl-L-argininal, N-acetyl-L-leucyl-N-{(2S)-5-[(diaminomethylidene)amino]-1-oxopentan-2-yl}-L-leucinamide, Nk-381, Valeramide, 2-(2-acetamido-4-methylvaleramido)-N-(1-formyl-4-guanidinobutyl)-4-methyl-, L-Leucinamide, N-acetyl-L-leucyl-N-[(1S)-4-[(aminoiminomethyl)amino]-1-formylbutyl]-, sulfate (2:1), L-Leucinamide, N-acetyl-L-leucyl-N-[4-[(aminoiminomethyl)amino]-1-formylbutyl]-, (S)-, sulfate (2:1)

Description

Leupeptin is a protein inhibitor that binds to the ubiquitin ligases and inhibits their activity. It has been shown to inhibit the transcriptional regulation of gene expression, which is important in cancer, chronic oral administration, and experimental models. Leupeptin also blocks the binding of proteins to DNA in cell culture and animal models. This leads to decreased production of fatty acids, which are needed for cellular growth and function. Leupeptin also has an anti-depressant effect by blocking the transcriptional regulation of gene expression for serotonin receptors.

• Brand: Biosynth

Chemical properties

• Molecular weight: 475.59 g/mol
• Formula: C₂₀H₃₈N₆O₄•(H₂SO₄)₀
• Purity: Min. 90.0 Area-%
• Color/Form: White Powder