Lithium amide

CAS: 7782-89-0

Ref. 3D-FL45315

Product Information

• Name: Lithium amide
• Brand: Biosynth
• Description: Lithium amide is a cholesterol ester transfer inhibitor that is used to treat infectious diseases. It prevents the accumulation of cholesterol in the brain and other tissues. Lithium amide has been shown to inhibit bacterial growth by binding to DNA-dependent RNA polymerase, thereby preventing transcription and replication. The high frequency of human activity has been shown using a patch-clamp technique on human erythrocytes. This active form is metabolized through a number of metabolic transformations, including hydrolysis by esterases or glucuronidases, oxidation by cytochrome P450 enzymes, reduction by glutathione reductase, or conjugation with glucuronic acid. Lithium amide also specifically binds to markers expressed at high levels in Mycobacterium tuberculosis strains (e.g., ESX-1 secretion system protein) and inhibits cell growth in culture.

Chemical properties

• Molecular weight: 22.96 g/mol
• Formula: LiNH₂