Labetalol hydrochloride

CAS: 32780-64-6

Ref. 3D-FL61512

Product Information

• Name: Labetalol hydrochloride
• Synonyms: 2-Hydroxy-5-{1-Hydroxy-2-[(4-Phenylbutan-2-Yl)Amino]Ethyl}Benzamide, 2-Hydroxy-5-{1-Hydroxy-2-[(4-Phenylbutan-2-Yl)Amino]Ethyl}Benzamide Hydrochloride (1:1), AH 5158 hydrochloride, Ah 5158A, Amipress, Benzamide, 2-hydroxy-5-[1-hydroxy-2-[(1-methyl-3-phenylpropyl)amino]ethyl]-, hydrochloride (1:1), Benzamide, 2-hydroxy-5-[1-hydroxy-2-[(1-methyl-3-phenylpropyl)amino]ethyl]-, monohydrochloride, Ipolab, Labelol, Labetalol HCl, Labetalol Hydrochoride, Labracol, NSC 290312, Normodyne, Presdate, Pressalolo, Salicylamide, 5-[1-hydroxy-2-[(1-methyl-3-phenylpropyl)amino]ethyl]-, monohydrochloride, Sch 15719W, Trandate, Vescal

Description

Labetalol is a beta-adrenergic blocker that inhibits the binding of epinephrine to beta-adrenergic receptors. It has been shown to inhibit the activity of p-glycoprotein (P-gp) and prevent the movement of drugs out of cells. Labetalol also affects the activity of enzymes such as CYP3A4, CYP2D6, CYP2C9, and CYP2C19, which are responsible for metabolizing many different drugs. This drug also has a direct effect on cardiac function. Labetalol is used in treatment of high blood pressure, but should not be used in pregnant women because it can cause fetal harm. Labetalol may also interact with other cardiovascular medications (e.g., beta blockers).

• Brand: Biosynth

Chemical properties

• Molecular weight: 364.87 g/mol
• Formula: C₁₉H₂₅ClN₂O₃
• Purity: 95%Nmr
• Color/Form: White Powder