(-)-Lycorine

CAS: 476-28-8

Ref. 3D-FL65705

Product Information

• Name: (-)-Lycorine
• Synonyms: (1S,2S,12bS,12cS)-2,4,5,7,12b,12c-hexahydro-1H-[1,3]dioxolo[4,5-j]pyrrolo[3,2,1-de]phenanthridine-1,2-diol, 1H-[1,3]Dioxolo[4,5-j]pyrrolo[3,2,1-de]phenanthridine-1,2-diol, 2,4,5,7,12b,12c-hexahydro-, (1S,2S,12bS,12cS)-, 1H-[1,3]Dioxolo[4,5-j]pyrrolo[3,2,1-de]phenanthridine-1,2-diol, 2,4,5,7,12b,12c-hexahydro-, [1S-(1α,2β,12bβ,12cα)]-, 3,3a-Didehydrolycoran-1alpha,2beta-diol, 3,3a-Didehydrolycoran-1α,2β-diol, 3,4-Didehydro-11,12-[methylenebis(oxy)]galanthan-1α,2β-diol, Amarylline, Galanthan-1,2-diol, 3,12-didehydro-9,10-(methylenebis(oxy))-, (1-alpha,2-beta)- (9CI), Galanthan-1,2-diol, 3,12-didehydro-9,10-[methylenebis(oxy)]-, (1α,2β)-, Galanthidine, Licorine, Lycoran-1-alpha,2-beta-diol, 3,3-alpha-didehydro-, Lycoran-1alpha,2beta-diol, 3,3a-didehydro- (8CI), Lycoran-1α,2β-diol, 3,3a-didehydro-, NSC 683873, Narcissin, Narcissine, Nsc 401360

Description

(-)-Lycorine is a natural compound that belongs to the group of alkaloids. It is found in plants such as the wolfberry, and has shown inhibitory properties against squamous cell carcinoma. (-)-Lycorine has been shown to induce apoptosis in Hl-60 cells by inhibiting mitochondrial functions and triggering epithelial mesenchymal transition. This compound also inhibits opportunistic fungal growth, including Candida albicans and Saccharomyces cerevisiae. (-)-Lycorine has been shown to have cytotoxic effects on cancer tissues, which may be caused by its ability to inhibit complex enzymes involved in cancer cell proliferation. (-)-Lycorine is structurally related to lycorine, an alkaloid from the plant Lycopodium serratum that can promote pluripotent stem cells.

• Brand: Biosynth

Chemical properties

• Molecular weight: 287.31 g/mol
• Formula: C₁₆H₁₇NO₄
• Purity: Min. 95%
• Color/Form: Powder