Leptomycin B
CAS:
Ref. 3D-FL75164
5mg
547.00€
10mg
748.00€
25mg
863.00€
50mg
1,085.00€
100mg
1,410.00€
Product Information
Name:Leptomycin B
Brand:Biosynth
Description:Leptomycin B is a bacterial secondary metabolite, which is derived from the bacterium Streptomyces sp. This compound is a potent nuclear export inhibitor with a mechanism of action that targets and inhibits the export receptor CRM1 (Chromosomal Maintenance 1), also known as Exportin 1. By binding irreversibly to CRM1, Leptomycin B prevents the nuclear export of proteins and RNA, disrupting the nuclear-cytoplasmic transport essential for cell function.
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Chemical properties
Molecular weight:540.73 g/mol
Formula:C33H48O6
Purity:Min. 95%
Technical inquiry about: Leptomycin B
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