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2-Mercaptopurine
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2-Mercaptopurine

CAS: 28128-19-0

Ref. 3D-FM02961

10mg
136.00 €
25mg
195.00 €
50mg
775.00 €
100mg
1,033.00 €
Estimated delivery in United States, on Thursday 16 Jan 2025

Product Information

Name:
2-Mercaptopurine
Synonyms:
  • 2-Thiopurine2-Purinethiol
  • 1,3-Dihydro-2H-purine-2-thione
  • 1H-Purine-2-thiol
  • 2-Thiopurine
  • 2H-Purine-2-thione, 1,3-dihydro-
  • 2H-Purine-2-thione, 1,3-dihydro- (9CI)
  • 2H-Purine-2-thione, 3,9-dihydro-
  • 3,5-dihydro-2H-purine-2-thione
  • 3,7-dihydro-2H-purine-2-thione
  • 5-Mercaptopurine
  • See more synonyms
  • Nsc 23720
  • Purine-2(3H)-thione
  • Purine-2-thiol
  • Purine-2-thione
  • 3,9-Dihydro-2H-purine-2-thione
Description:

2-Mercaptopurine (2MP) is a thiopurine drug that is used to treat bowel disease. 2MP inhibits the activity of methyltransferase, which is an enzyme that converts 6-mercaptopurine to 6-thioguanine. This process prevents the conversion of 6-thioguanine into 6-thiouric acid, which is an intermediate in the synthesis of thymine nucleotides. 2MP also inhibits the binding of atp-binding cassette transporter proteins to DNA and blocks the incorporation of purines into RNA and DNA. The drug has been shown to be effective in treating squamous cell carcinoma and other diseases with a high level of activity. 2MP has been shown to be metabolized by erythrocyte polymerase chain reaction and can be detected in biological samples.

Notice:
Our products are intended for lab use only. For any other use, please contact us.
Brand:
Biosynth
Long term storage:
Notes:

Chemical properties

Molecular weight:
152.18 g/mol
Formula:
C5H4N4S
Purity:
Min. 95%
Color/Form:
Powder
InChI:
InChI=1S/C5H4N4S/c10-5-6-1-3-4(9-5)8-2-7-3/h1-2H,(H2,6,7,8,9,10)
InChI key:
InChIKey=HDBQZGJWHMCXIL-UHFFFAOYSA-N
SMILES:
S=c1ncc2[nH]cnc2[nH]1
MDL:
Melting point:
Boiling point:
Flash point:
Density:
Concentration:
EINECS:
Merck:
HS code:

Hazard Info

UN Number:
EQ:
Class:
H Statements:
P Statements:
Forbidden to fly:
Hazard Info:
Packing Group:
LQ:

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