Product Information
Name:2-Mercaptopyridine
Synonyms:
- Thio-2-pyridine2-Thiopyridine
Brand:Biosynth
Description:2-Mercaptopyridine is a quinone that has been used as an inhibitor of the HIV reverse transcriptase enzyme. It binds to the active site of the enzyme and inhibits its activity by forming a stable covalent bond with two cysteine residues in the enzyme. The molecule is stabilized by two adjacent sulfide bonds, which form a six-membered ring with three nitrogen atoms and one oxygen atom. This ring coordinates to the zinc ion in the active site of the enzyme. 2-Mercaptopyridine has also been found to be effective against methicillin-resistant Staphylococcus aureus (MRSA) and Mycobacterium tuberculosis. 2-Mercaptopyridine binds to DNA at positions where it is complementary to guanine or adenine nucleotides, thus preventing RNA synthesis and replication.
Notice:Our products are intended for lab use only. For any other use, please contact us.
Chemical properties
Molecular weight:111.17 g/mol
Formula:C5H5NS
Purity:Min. 95%
Color/Form:Powder
InChI:InChI=1S/C5H5NS/c7-5-3-1-2-4-6-5/h1-4H,(H,6,7)
InChI key:InChIKey=WHMDPDGBKYUEMW-UHFFFAOYSA-N
SMILES:S=c1cccc[nH]1
Technical inquiry about: 2-Mercaptopyridine
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