1-Methylcyclopropanesulphonamide

CAS: 669008-26-8

Ref. 3D-FM07916

Product Information

• Name: 1-Methylcyclopropanesulphonamide
• Synonyms: 1-Methyl-Cyclopropanesulfonic Acid Amide, 1-Methyl-cyclopropylsulfonamide, 1-Methylcyclopropanesulfonamide, Cyclopropanesulfonamide, 1-Methyl-, 1-Methylcyclopropane-1-sulfonamide

Description

1-Methylcyclopropanesulphonamide is a drug that inhibits the activity of serine protease. It has been shown to inhibit the replication of hepatitis C virus and HIV, while also inhibiting the enzymatic activity of human leukocyte elastase. This drug has a molecular weight of 226.3 g/mol and is soluble in water. 1-Methylcyclopropanesulphonamide is used for treatment of viral hepatitis, such as chronic active hepatitis, acute hepatitis, and fulminant hepatic failure. It is also used to treat inflammatory bowel disease and rheumatoid arthritis.
1-Methylcyclopropanesulphonamide binds reversibly to the enzyme's active site with an affinity constant (K) of 7 x 10 M at 37°C and pH 7.5 under conditions where the compound exists in its free form or as a protonated molecule. The binding mode appears to be hydrophobic in nature,

• Brand: Biosynth

Chemical properties

• Molecular weight: 135.19 g/mol
• Formula: C₄H₉NO₂S
• Purity: Min. 95%
• Color/Form: Powder
• InChI: InChI=1S/C4H9NO2S/c1-4(2-3-4)8(5,6)7/h2-3H2,1H3,(H2,5,6,7)
• InChI key: InChIKey=ATJVVVCODTXRAE-UHFFFAOYSA-N
• SMILES: CC1(S(N)(=O)=O)CC1