3-Methyladenine

CAS: 5142-23-4

Ref. 3D-FM08029

Product Information

• Name: 3-Methyladenine
• Synonyms: 3-MA6-Amino-3-methylpurine, 3-Ma, 3-Methyl-3H-purin-6-ylamine, 3-Methyl-6-aminopurine, 3-Methylpurin-6-amine, 3-methyl-3H-purin-6-amine, 3H-Purin-6-amine, 3-methyl-, 6-Amino-3-methylpurine, Adenine, 3-methyl-, Brn 0146087, N³-Methyladenine, Nsc 66389

Description

3-Methyladenine is a glycosylase that cleaves the glycosidic bond between the 3rd and 4th carbon of the ribose ring of the nucleotide 3-methyladenine. It also has synergistic effects with other agents that induce autophagy, such as rapamycin, and increases the expression of a response element in mouse monoclonal antibody. 3-Methyladenine inhibits growth factor-β1 and neuronal death by inducing apoptosis in cells overexpressing nuclear DNA polymerase. This drug is also used to study apoptosis by using a model system.

• Brand: Biosynth

Chemical properties

• Molecular weight: 149.15 g/mol
• Formula: C₆H₇N₅
• Purity: Min. 90 Area-%
• Color/Form: Powder
• InChI: InChI=1S/C6H7N5/c1-11-3-10-5(7)4-6(11)9-2-8-4/h2-3,7H,1H3,(H,8,9)
• InChI key: InChIKey=ZPBYVFQJHWLTFB-UHFFFAOYSA-N
• SMILES: Cn1cnc(=N)c2[nH]cnc21